Introduction
 
The term "myeloid" derives from the Greek myelos, meaning "marrow." Sometimes the term "myeloid" is used to describe hematological conditions or diseases not involving the lymphoid tissues or lymphocytes. "Myeloid" is also used to describe disorders primarily involving granulocytes (neutrophils, eosinophils, or basophils) and monocytes. Tissue macrophages (histiocytes), Langerhans cells, and interdigitating dendritic cells also arise from monocytic progenitors or precursors. Other important immunoregulatory dendritic cell types and mast cells derive from marrow progenitors that are distinct from myeloid and monocytic progenitors. This chapter covers disorders of granulocytes, monocytes, histiocytes, dendritic cells, and mast cells. The myeloproliferative disorders (ie, . . . [Full Text of this Article]


Granulocytes: neutrophils, eosinophils, and basophils
 
Granulopoiesis
Neutrophil release from the bone marrow
Neutrophil extravasation

Monocytes and tissue histiocytes
 

Dendritic antigen-presenting cells
 

Mast cells
 

Neutrophilia
 

Neutropenia
 
Congenital or inherited neutropenia
Severe congenital neutropenia (Kostmann syndrome)
Cyclic neutropenia
Shwachman–Diamond Syndrome
WHIM syndrome
Chédiak–Higashi syndrome
Neonatal alloimmune neutropenia
Primary autoimmune neutropenia
Secondary autoimmune neutropenia
Large granular lymphocyte leukemia
Nonimmune chronic idiopathic neutropenia
Neutropenia due to idiosyncratic drug reactions
Chemotherapy-induced neutropenia

Disorders of neutrophil function
 
Myeloperoxidase deficiency
Leukocyte adhesion deficiency
Hyperimmunoglobulin E syndrome
Neutrophil-specific granule deficiency
Chronic granulomatous disease
Familial Mediterranean fever

Monocytosis
 

Disorders of histiocytes and dendritic cells
 
Hemophagocytic lymphohistiocytosis
Diagnosis and prognosis
Treatment
Langerhans cell histiocytosis
Diagnosis
Treatment

Mastocytosis
 
Diagnosis of CM and SM
Treatment of CM and SM